Ukucindezelwa Kwesistimu Yamasosha omzimba
Ucwaningo olusha olushicilelwe ku Ijenali YaseMelika Yomsuka Wokuphefumula Nokubaluleka Kokunakekela ithole ukuthi ama-e-cigarettes akhiwe ngosawoti we-nicotine anemiphumela yokunciphisa umzimba kubasebenzisi. Nakuba imiphumela yezempilo yesikhathi eside yalokhu kucindezela amasosha omzimba kusazophenywa, lokhu kufanele kwenze abasebenzisi be-e-cigarette bakhathazeke.
Lolu cwaningo olusha lwagunyazwa yiNational Institute of Health futhi lwenziwa ithimba lochwepheshe abavela ku Isikole Sezokwelapha se-UNC. Ithimba belizimisele ukuphenya ngomthelela wezempilo wama-vaper “esizukulwane sesine” kubasebenzisi. Lawa ngamadivayisi esimanje adumile afaka umphunga njengemikhiqizo yeJuul.
Ukuqedela uphenyo lwalo ithimba lososayensi bezokwelapha laqoqa amasampula emaqenjini amane ahlukene. Lawa maqembu kwakungalezi: abasebenzisi bomkhiqizo we-vaping wesizukulwane sesine, abasebenzisi bomkhiqizo we-vaping wesizukulwane sesithathu, ababhemayo bakagwayi, kanye nalabo abangabhemi. Ama-biomarker amaningi okuvuvukala abe eselinganiswa ngesampula yesikhwehlela ngasinye.
Ucwaningo luthole ukuthi amasampula avela kubasebenzisi be-e-cigarette besizukulwane sesine aqukethe amazinga aphezulu ngokungavamile amaseli e-bronchial epithelial. Lawa maseli avame ukutholakala kumasampula avela kubantu abalimele endleleni yomoya futhi awahlotshaniswa nokusetshenziswa kukagwayi.
Ucwaningo luphinde lwathola ukuthi amasampula avela kubasebenzisi be-vaper besizukulwane sesine aqukethe amazinga aphansi ezinhlobonhlobo zamaseli omzimba anjenge-VEGF, MMP-2, MCP-1, CRP, kanye ne-uteroglobin phakathi kwabanye. Leli bekuyizinga eliphansi kunawo wonke amasampula. Lokhu kubonise ukuthi amadivaysi e-vaping esizukulwane sesine adlale indima ekucindezeleni amasosha omzimba abasebenzisi.
Ngokusho kuka-Elise Hickman umcwaningi oholayo, lapho ehlola amasampula ewonke, labo abavela kubasebenzisi be-e-cigarette besizukulwane esilwa babe noshintsho olukhulu kakhulu uma beqhathaniswa namanye amaqembu okuhlola. Lokhu kukhombise ushintsho olukhulu ku-immune homeostasis yaleli qembu uma kuqhathaniswa namanye amaqembu ocwaningweni.
Abacwaningi basheshe baqaphela ukuthi abakutholile akuzange kuxhumanise ukucindezelwa kwamasosha omzimba kunoma iyiphi inkinga ethile yezempilo. Ngakho-ke kubalulekile ukuthi amalungu omphakathi aqaphele ukuthi nakuba ukusetshenziswa kwe-e-cigarette yesizukulwane sesine kwatholakala ukuthi kunomthelela emasosheni omzimba omzimba ucwaningo alukwazanga ukuhlobanisa ukusetshenziswa kwalawo madivaysi nanoma yisiphi isifo esithile esifana ne-emphysema noma umdlavuza.
Lokhu akusho ukuthi izifundo zesikhathi esizayo zingase zingasitholi isixhumanisi. Kodwa-ke, ucwaningo lwamanje lwalunesithakazelo kuphela ekutholeni umthelela wokusebenzisa imikhiqizo ye-e-cigarette kumasosha omzimba omzimba. Okutholakele kwakukhethekile ukuthi ngenkathi ezinye i-e-cigarettes kanye nemikhiqizo kagwayi ingenawo umthelela omkhulu kumasosha omzimba, i-e-cigarette yesizukulwane sesine yenza. Imiphumela yezempilo yesikhathi eside yalokhu ayaziwa namanje.
U-Ilona Jaspers, omunye wabacwaningi eqenjini elenze lolu cwaningo uyachaza ukuthi “akunakwenzeka ukwazi ukuthi i-vaping inciphisa ingozi yomdlavuza noma ezinye izimo eziningi zesikhathi eside.” Lokhu kungenxa yokuthi kuthatha isikhathi ukuthola ukuhlobana phakathi komkhiqizo nesifo esithile. Isibonelo, kwathatha iminyaka engaphezu kwengu-60 yocwaningo ukuthola ukuthi ukubhema imikhiqizo kagwayi kubangela umdlavuza. Noma kunjalo, izifundo eziningi zizodingeka ukuze kutholwe ukuxhumana phakathi kokucindezelwa komzimba okutholakala kulolu cwaningo nanoma yisiphi isifo esaziwayo. Abacwaningi bakholelwa ukuthi ucwaningo olwengeziwe luyadingeka emikhiqizweni ye-e-cigarette ukuze wazise kangcono umphakathi ngezingozi zabo.
